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In the event of acute accidental overdosetreatment consists of supportive and symptomatic measuresWithin the first hour after ingestionactivated charcoal may be administered.

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Co-administration of the following drugs with ketoconazole is contraindicateddofetilidequinidinepimozidecisaprideKetoconazole can cause elevated plasma concentrations of these drugs and may prolong QT intervalssometimes resulting in life-threatening ventricular dysrhythmias such as torsades de pointesSee CONTRAINDICATIONSWARNINGSand PRECAUTIONSDRUG INTERACTIONS sections.

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