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AffiliationCentre for Cognitive Ageing and Cognitive EpidemiologyDepartment of PsychologyUniversity of EdinburghEdinburghUnited Kingdom.

AffiliationMRC Human GeneticsInstitute of Genetics and Molecular MedicineUniversity of EdinburghEdinburghUnited Kingdom.

SNPs reaching genome-wide significance are shown in greenThey all belong to the SERPINA gene cluster.

Characteristics of study populations contributing to the SNP association analyses with FEV1.

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optionally the serpina-1 polypeptide and or albumin polypeptide levels in urine are measured using an immunological assay e.