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Before taking tetracyclinetell your doctor or pharmacist if you are allergic to itor to other tetracyclinese.gdoxycyclineminocyclineor if you have any other allergiesThis product may contain inactive ingredientswhich can cause allergic reactions or other problemsTalk to your pharmacist for more details.

Hepatic side effects have included increased liver enzyme levelshepatotoxicityliver failureand bile duct paucity with prolonged cholestasisThese may be dose-relatedRef]

There have been several cases of esophageal ulcers associated with oral tetracycline therapyIn each casethe patient had taken the medication just before bedtime with only small amounts of liquid and reported severe retrosternal pain and painful swallowing shortly thereafterThe ulcers resolved spontaneously after discontinuation of tetracycline therapyTo minimize esophageal irritationpatients should be advised to avoid taking tetracycline just before retiring and to take the medication with plenty of water.

Musculoskeletal side effects have included adult tooth discolorationenamel hypoplasiaand a decrease in linear skeletal growth rateTetracyclinethe active ingredient contained in Panmycinshould not be administered to pregnant women or children less than 12 years of ageRef]

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